BACKGROUND/AIMS: microRNAs (miRNAs) are small noncoding RNAs that regulate cognate mRNAs post-transcriptionally.Human embryonic stem cells (hESC), which exhibit the characteristics of pluripotency and self-renewal, may serve as a model to study the role of miRNAs in early human development.We aimed to determine whether endodermally-differentiated h
Comparison of facet joint violation in lumbar posterior spinal instrumentation using different techniques including cortical bone trajectory
Study background: A retrospective study to compare the rate of facet joint violation (FJV) in lumbar posterior spinal instrumentation using open pedicle screw, percutaneous pedicle screw, and cortical bone trajectory (CBT) technique.CBT is a new posterior spinal instrumentation technique in which a more caudal entry point can minimize iatrogenic da
PRESERVATIVE TREATMENT OF GREEN POPLAR POLES BY USING TIRE -TUBE METHOD
In this study, green round poles of Populus nigra L.var.italica were treated with Celcure by using Tire - Tube method.After felling and sizing trees, thick - end of poles (about 15 cm.) were debarked and a section of tire inner Tube was grand love red heart reposado tequila fastened around the debarked end of the fresh - cut poles and bound tightly
Comparative study on the performance of protein and synthetic-based foaming agents used in foamed concrete
Foamed 100w products concrete is a composite material with a density that is significantly lower than standard concrete.The property of being lightweight is due to tiny air voids produced by the addition of foaming agents in cement paste.The purpose of this research is to experimentally investigate the influence of various types of foaming agents i
Abnormal repression of SHP-1, SHP-2 and SOCS-1 transcription sustains the activation of the JAK/STAT3 pathway and the progression of the disease in multiple myeloma.
Sustained activation of JAK/STAT3 signaling pathway is classically described in Multiple Myeloma (MM).One explanation could be the silencing of the JAK/STAT suppressor genes, through the hypermethylation of SHP-1 and SOCS-1, previously demonstrated in MM cell lines or in whole bone marrow aspirates.The link between such suppressor gene silencing an